Publications

Lab publications on ctDNA:
(See also at https://scholar.google.com/citations?user=VzqZOSsAAAAJ)

 

2017

K. M. Patel, K. E. van der Vos, C. G. Smith, F. Mouliere, D. Tsui, J. Morris, D. Chandrananda, F. Marass, D. van den Broek, D. E. Neal, V. J. Gnanapragasam, T. Forshew, B. W. van Rhijn, C. E. Massie, N. Rosenfeld & M. S. van der Heijden
Association Of Plasma And Urinary Mutant DNA With Clinical Outcomes In Muscle Invasive Bladder Cancer
Scientific Reports 7, Article number: 5554 (2017)
doi:10.1038/s41598-017-05623-3. Full text

 

F Mouliere, A. M. Piskorz, D. Chandrananda, E. Moore, J. Morris, C. G. Smith, T. Goranova, K. Heider, R. Mair, A. Supernat, I. Gounaris, S. Ros, J. C. M. Wan, M. Jimenez-Linan, D. Gale, K. Brindle, C. E. Massie, C. A. Parkinson, J. D. Brenton, N. Rosenfeld
Selecting Short DNA Fragments In Plasma Improves Detection Of Circulating Tumour DNA
bioRxiv. Posted May 5, 2017.
doi: 10.1101/134437. Full text

 

Wan JCM, Massie C, Garcia-Corbacho J, Mouliere F, Brenton JD, Caldas C, Pacey S, Baird S, Rosenfeld N.
Liquid biopsies come of age: towards implementation of circulating tumour DNA
Nat Rev Cancer. 2017 Apr;17(4):223-238. doi: 10.1038/nrc.2017.7. Review.
Full text / PDF (free via SharedIt)

 

2016

Mouliere, F., and Tsui, D.W.Y.
Cell-Free DNA: Beyond Noninvasive Prenatal Testing.
Clinical Laboratory News. 2016. Full text

 

Marass F, Mouliere F, Yuan K, Rosenfeld N, Markowetz F.
A phylogenetic latent feature model for clonal deconvolution
Annals of Applied Statistics arXiv:1604.01715 Full text


Parkinson CA, Gale D, Piskorz AM, Biggs H, Hodgkin C, Addley H, Freeman S, Moyle P, Sala E, Sayal K, Hosking K, Gounaris I, Jimenez-Linan M, Earl HM, Qian W, Rosenfeld N, Brenton JD.
Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
PLOS Medicine. 2016 13(12): e1002198. Full text

 

2015

Murtaza M, Dawson SJ, Pogrebniak K, Rueda OM, Provenzano E, Grant J, Chin SF, Tsui DW, Marass F, Gale D, Ali HR, Shah P, Contente-Cuomo T, Farahani H, Shumansky K, Kingsbury Z, Humphray S, Bentley D, Shah SP, Wallis M, Rosenfeld N, Caldas C.
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer
Nat Commun. 2015 Nov 4;6:8760. doi: 10.1038/ncomms9760. Full text

 

K.M. Patel and D.W.Y. Tsui.
The translational potential of circulating tumour DNA in oncology
Clinical Biochemistry, Volume 48, Issue 15, October 2015, Pages 957–961. Full text

 

Mouliere F and Rosenfeld N.
Circulating tumor-derived DNA is shorter than somatic DNA in plasma.
Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3178-9. doi: 10.1073/pnas.1501321112. Full text

 

2013

M. Murtaza*, S.-J. Dawson*, D. W. Y. Tsui*, D. Gale, T. Forshew, A. M. Piskorz, C. Parkinson, S.-F. Chin, Z. Kingsbury, A. S.C. Wong, F. Marass, S. Humphray, J. Hadfield, D. Bentley, T. M. Chin, J. D. Brenton@, C. Caldas@, N. Rosenfeld@.
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA.
Nature (2013). DOI:10.1038/nature12065. Published online 7/4/13. Full text
Covered by: “Community Corner” in Nature Medicine; GenomeWeb Clinical Sequencing News;
News items: The TimesScotsman; CRUK blog / press release / opinion piece; University of Cambridge press release.

 

S.-J. Dawson*, D. W.Y. Tsui*, M. Murtaza, H. Biggs, O. M. Rueda, S.-F. Chin, M. J. Dunning, D. Gale, T. Forshew,
B. Mahler-Araujo, S. Rajan, S. Humphray, J. Becq, D. Halsall, M. Wallis, D. Bentley, C. Caldas@, N. Rosenfeld@.
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer.  N Engl J Med. (2013).
DOI: 10.1056/NEJMoa1213261. Published online 13/3/13. Full textReprint
Covered by: Nature News, Editor’s Choice at Science Translational Med, Research Highlights at Nat Rev Clin Onc, Lancet Oncology News; Radio and Video interview with Dr. Dana Tsui at MDFM/audio-journal of oncology. News items: The TelegraphDaily MailUSA Today;  See also: GenomeWeb Daily; CRUK blog and press release.

 

2012

T. Forshew*, M. Murtaza*, C. Parkinson*, D. Gale*, D. W. Y. Tsui*, F. Kaper, S.-J. Dawson,
A. M. Piskorz, M. Jimenez-Linan, D. Bentley, J. Hadfield, A. P. May, C. Caldas, J. D. Brenton@,
N. Rosenfeld@
Noninvasive identification and monitoring of cancer mutations by targeted
deep sequencing of plasma DNA.
Sci. Transl. Med. 4, 136ra68 (2012). Abstract / Full text / Reprint.
News items: The Telegraph, Daily Mail, LA TimesTimes of India.
See also: GenomeWeb Daily / Clinical Sequencing News; CRUK blog, press release and video.

 

 

Additional/full lists of publications by individual group members:

Nitzan’s publications: PubMed Google Scholar.

See publications by other group members in their personal pages.