See also at our Google Scholar Profile


Gale D, Heider K, Ruiz-Valdepenas A, et al. Residual ctDNA after treatment predicts early relapse in patients with early-stage non-small cell lung cancer. Ann Oncol. 2022 May;33(5):500-510. doi: 10.1016/j.annonc.2022.02.007. Epub 2022 Mar 17. PMID: 35306155. [PubMed]


Markus H, Chandrananda D, Moore E, et al. Refined characterization of circulating tumor DNA through biological feature integration. Sci Rep. 2022;12(1):1928. Published 2022 Feb 4. doi:10.1038/s41598-022-05606-z. [PubMed]


Hudecova I, Smith CG, Hänsel-Hertsch R, et al. Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA. Genome Res. 2022 Feb;32(2):215-227. doi: 10.1101/gr.275691.121. Epub 2021 Dec 20. PMID: 34930798; PMCID: PMC8805718. [PubMed]


Mouliere F, Smith CG, Heider K, et al. Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients. EMBO Mol Med. 2021 Aug 9;13(8):e12881. doi: 10.15252/emmm.202012881. Epub 2021 Jul 22. PMID: 34291583; PMCID: PMC8350897. [PubMed]


Biasci D, Smoragiewicz M, Connell CM, et al. CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28960-28970. doi: 10.1073/pnas.2013644117. [PubMed]


Gill, A. B., Rundo, L., Wan, J. C. M., et al. Correlating Radiomic Features of Heterogeneity on CT with Circulating Tumor DNA in Metastatic Melanoma. Cancers, 12(12). doi:10.3390/cancers12123493. [Full text]


Wan JCM*, Heider K*, Gale D, et al. ctDNA monitoring using patient-specific sequencing and integration of variant reads. Sci Transl Med. 2020 Jun 17;12(548). [PubMed] [Free Access PDF] [Free Access Full Text]


Heider K, Wan JCM, Hall J, et al. Detection of ctDNA from Dried Blood Spots after DNA Size Selection. Clin Chem. 2020;66(5):697-705. doi:10.1093/clinchem/hvaa050. [PubMed]


Smith CG, Moser T, Mouliere F, et al. Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors. Genome Med. 2020;12(1):23. Published 2020 Feb 28. doi:10.1186/s13073-020-00723-8. [PubMed]


Mair R, Mouliere F, Smith CG, et al. Measurement of Plasma Cell-Free Mitochondrial Tumor DNA Improves Detection of Glioblastoma in Patient-Derived Orthotopic Xenograft Models. Cancer Res. 2019;79(1):220-230. doi:10.1158/0008-5472.CAN-18-0074. [PubMed]


Tsui DWY, Murtaza M, Wong ASC, et al. Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer. EMBO Mol Med. 2018;10(6):e7945. doi:10.15252/emmm.201707945. [PubMed]


Risberg B, Tsui DWY, Biggs H, et al. Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients. J Mol Diagn. 2018;20(6):883-892. doi:10.1016/j.jmoldx.2018.07.005. [PubMed]


Mouliere F, Mair R, Chandrananda D, et al. Detection of cell-free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients. EMBO Mol Med. 2018;10(12):e9323. doi:10.15252/emmm.201809323. [PubMed]


Mouliere F, Chandrananda D, Piskorz AM, et al. Enhanced detection of circulating tumor DNA by fragment size analysis. Sci Transl Med. 2018;10(466):eaat4921. doi:10.1126/scitranslmed.aat4921. [PubMed]


Mock A, Murphy S, Morris J, Marass F, Rosenfeld N, Massie C. CVE: an R package for interactive variant prioritisation in precision oncology. BMC Med Genomics. 2017;10(1):37. Published 2017 May 25. doi:10.1186/s12920-017-0261-6. [PubMed]


K. M. Patel, K. E. van der Vos, C. G. Smith, F. Mouliere, D. Tsui, J. Morris, D. Chandrananda, F. Marass, D. van den Broek, D. E. Neal, V. J. Gnanapragasam, T. Forshew, B. W. van Rhijn, C. E. Massie, N. Rosenfeld & M. S. van der Heijden
Association Of Plasma And Urinary Mutant DNA With Clinical Outcomes In Muscle Invasive Bladder Cancer
Scientific Reports 7, Article number: 5554 (2017)
doi:10.1038/s41598-017-05623-3. [Full text]


F Mouliere, A. M. Piskorz, D. Chandrananda, E. Moore, J. Morris, C. G. Smith, T. Goranova, K. Heider, R. Mair, A. Supernat, I. Gounaris, S. Ros, J. C. M. Wan, M. Jimenez-Linan, D. Gale, K. Brindle, C. E. Massie, C. A. Parkinson, J. D. Brenton, N. Rosenfeld
Selecting Short DNA Fragments In Plasma Improves Detection Of Circulating Tumour DNA
bioRxiv. Posted May 5, 2017.
doi: 10.1101/134437. [Full text]


Wan JCM, Massie C, Garcia-Corbacho J, Mouliere F, Brenton JD, Caldas C, Pacey S, Baird S, Rosenfeld N.
Liquid biopsies come of age: towards implementation of circulating tumour DNA
Nat Rev Cancer. 2017 Apr;17(4):223-238. doi: 10.1038/nrc.2017.7. Review.
[Full text]  [PDF (free via SharedIt)]


Mouliere, F., and Tsui, D.W.Y.
Cell-Free DNA: Beyond Noninvasive Prenatal Testing.
Clinical Laboratory News. 2016. [Full text]


Marass F, Mouliere F, Yuan K, Rosenfeld N, Markowetz F.
A phylogenetic latent feature model for clonal deconvolution
Annals of Applied Statistics arXiv:1604.01715 [Full text]

Parkinson CA, Gale D, Piskorz AM, Biggs H, Hodgkin C, Addley H, Freeman S, Moyle P, Sala E, Sayal K, Hosking K, Gounaris I, Jimenez-Linan M, Earl HM, Qian W, Rosenfeld N, Brenton JD.
Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
PLOS Medicine. 2016 13(12): e1002198. [Full text]


Murtaza M, Dawson SJ, Pogrebniak K, Rueda OM, Provenzano E, Grant J, Chin SF, Tsui DW, Marass F, Gale D, Ali HR, Shah P, Contente-Cuomo T, Farahani H, Shumansky K, Kingsbury Z, Humphray S, Bentley D, Shah SP, Wallis M, Rosenfeld N, Caldas C.
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer
Nat Commun. 2015 Nov 4;6:8760. doi: 10.1038/ncomms9760. [Full text]


K.M. Patel and D.W.Y. Tsui.
The translational potential of circulating tumour DNA in oncology
Clinical Biochemistry, Volume 48, Issue 15, October 2015, Pages 957–961. [Full text]


Mouliere F and Rosenfeld N.
Circulating tumor-derived DNA is shorter than somatic DNA in plasma.
Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3178-9. doi: 10.1073/pnas.1501321112. [Full text]


M. Murtaza*, S.-J. Dawson*, D. W. Y. Tsui*, D. Gale, T. Forshew, A. M. Piskorz, C. Parkinson, S.-F. Chin, Z. Kingsbury, A. S.C. Wong, F. Marass, S. Humphray, J. Hadfield, D. Bentley, T. M. Chin, J. D. Brenton@, C. Caldas@, N. Rosenfeld@.
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA.
Nature (2013). DOI:10.1038/nature12065. Published online 7/4/13. [Full text]
Covered by: “Community Corner” in Nature Medicine; GenomeWeb Clinical Sequencing News;
News items: The TimesScotsman; CRUK blog / press release / opinion piece; University of Cambridge press release.


S.-J. Dawson*, D. W.Y. Tsui*, M. Murtaza, H. Biggs, O. M. Rueda, S.-F. Chin, M. J. Dunning, D. Gale, T. Forshew,
B. Mahler-Araujo, S. Rajan, S. Humphray, J. Becq, D. Halsall, M. Wallis, D. Bentley, C. Caldas@, N. Rosenfeld@.
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer.  N Engl J Med. (2013).
DOI: 10.1056/NEJMoa1213261. Published online 13/3/13. [Full text]  [Reprint]
Covered by: Nature News, Editor’s Choice at Science Translational Med, Research Highlights at Nat Rev Clin Onc, Lancet Oncology News; Radio and Video interview with Dr. Dana Tsui at MDFM/audio-journal of oncology. News items: The TelegraphDaily MailUSA Today;  See also: GenomeWeb Daily; CRUK blog and press release.


T. Forshew*, M. Murtaza*, C. Parkinson*, D. Gale*, D. W. Y. Tsui*, F. Kaper, S.-J. Dawson,
A. M. Piskorz, M. Jimenez-Linan, D. Bentley, J. Hadfield, A. P. May, C. Caldas, J. D. Brenton@,
N. Rosenfeld@
Noninvasive identification and monitoring of cancer mutations by targeted
deep sequencing of plasma DNA.
Sci. Transl. Med. 4, 136ra68 (2012). [Abstract]  [Full text]  [Reprint]
News items: The Telegraph, Daily Mail, LA TimesTimes of India.
See also: GenomeWeb Daily / Clinical Sequencing News; CRUK blog, press release and video.


Additional/full lists of publications by individual group members:

Nitzan’s publications: PubMed Google Scholar.

See publications by other group members in their personal pages.